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STOCK-RAISING AND VETERINARY

BIOLOGICAL PROPERTIES OF BACTERIOPHAGES IN RELATION TO MYCOBACTERIUM TUBERCULOSIS

N.S. Syrym* 1 , S.T. Nussupova 1 , S.T. Siyabekov 1 , M.А. Berdikulov 2 , К.Т. Maikhin 2

1 Kazakh National Agrarian Research University, Almaty; 2 RSE National reference center for veterinary

doi.org/10.37884/2-2021/6 pp. 52-61 Admitted 03.03.2022 Published 30.06.2021

Abstract

The study of the biological properties of bacteriophages is an important stage in the creation of biologics, phagoindication and phage identification of bacteria. The main sign of the action of phages on sensitive bacteria is their lysis, accompanied by the release of new phage virions into the environment.
Research has been conducted to study the basic biological properties of bacteriophages in relation to mycobacteria isolated from environmental objects and biological material.
All the phages studied had a titer of 107-109 by Appelman and 109-1010 by Grazia, had a pronounced specificity in relation to mycobacteria: M. bovis, M. tuberculosis, M. kansasii, M. avium, M. scrofulaseum, M. phlei, M. terrae, M. intracellulare, M. smegmatis and did not show activity against other mycobacteria species.
All these phages maintained their lytic activity for 2 months and were resistant to heating in the range of 50°C-70°C for 30 minutes. The phages were resistant to 10% chloroform solution for 45 min.

Mycobacterium, tuberculosis, bacteriophage, biological material strains, the objects of the external environment, antibacterial effect, culture.

01 Introduction

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02 References

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Citation Links

[1]2021. BIOLOGICAL PROPERTIES OF BACTERIOPHAGES IN RELATION TO MYCOBACTERIUM TUBERCULOSIS. Izdenister natigeler. 2 (90) (Jun. 2021), 52–61. DOI:https://doi.org/10.37884/2-2021/6.
(1)BIOLOGICAL PROPERTIES OF BACTERIOPHAGES IN RELATION TO MYCOBACTERIUM TUBERCULOSIS. Izdenister natigeler 2021, No. 2 (90), 52-61. https://doi.org/10.37884/2-2021/6.
BIOLOGICAL PROPERTIES OF BACTERIOPHAGES IN RELATION TO MYCOBACTERIUM TUBERCULOSIS. (2021). Izdenister Natigeler, 2 (90), 52-61. https://doi.org/10.37884/2-2021/6
BIOLOGICAL PROPERTIES OF BACTERIOPHAGES IN RELATION TO MYCOBACTERIUM TUBERCULOSIS. Izdenister natigeler, [S. l.], n. 2 (90), p. 52–61, 2021. DOI: 10.37884/2-2021/6. Disponível em: https://natsus.kaznaru.edu.kz/index.php/research/article/view/27. Acesso em: 15 sep. 2026.
“BIOLOGICAL PROPERTIES OF BACTERIOPHAGES IN RELATION TO MYCOBACTERIUM TUBERCULOSIS”. 2021. Izdenister Natigeler, no. 2 (90) (June): 52-61. https://doi.org/10.37884/2-2021/6.
“BIOLOGICAL PROPERTIES OF BACTERIOPHAGES IN RELATION TO MYCOBACTERIUM TUBERCULOSIS” (2021) Izdenister natigeler, (2 (90), pp. 52–61. doi:10.37884/2-2021/6.
[1]“BIOLOGICAL PROPERTIES OF BACTERIOPHAGES IN RELATION TO MYCOBACTERIUM TUBERCULOSIS”, Izdenister natigeler, no. 2 (90), pp. 52–61, Jun. 2021, doi: 10.37884/2-2021/6.
“BIOLOGICAL PROPERTIES OF BACTERIOPHAGES IN RELATION TO MYCOBACTERIUM TUBERCULOSIS”. Izdenister Natigeler, no. 2 (90), June 2021, pp. 52-61, https://doi.org/10.37884/2-2021/6.
“BIOLOGICAL PROPERTIES OF BACTERIOPHAGES IN RELATION TO MYCOBACTERIUM TUBERCULOSIS”. Izdenister natigeler, no. 2 (90) (June 30, 2021): 52–61. Accessed September 15, 2026. https://natsus.kaznaru.edu.kz/index.php/research/article/view/27.
1.BIOLOGICAL PROPERTIES OF BACTERIOPHAGES IN RELATION TO MYCOBACTERIUM TUBERCULOSIS. Izdenister natigeler [Internet]. 2021 Jun. 30 [cited 2026 Sep. 15];(2 (90):52-61. Available from: https://natsus.kaznaru.edu.kz/index.php/research/article/view/27
1.BIOLOGICAL PROPERTIES OF BACTERIOPHAGES IN RELATION TO MYCOBACTERIUM TUBERCULOSIS. Izdenister natigeler. 2021;(2 (90):52-61. doi:10.37884/2-2021/6