ШКАЛЫ PIRO И SAPS ДЛЯ ПРОГНОЗА ИСХОДА ЗАБОЛЕВАНИЯ У КОШЕК

Сергей Лаптев; Василий Павлович

doi:10.37884/3-2024/05

Abstract

Reliable prediction of sepsis is an important clinical problem in medicine and veterinary medicine because of the high morbidity and mortality from sepsis complications. Studying the etiology of septic complications in feline panleukopenia, we adapted the PIRO and SAPS diagnostic scales proposed to assess the prognosis of sepsis in clinical veterinary medicine. Multistage assessment of the clinical condition of animals allows us to identify animals with increased risk of complications in the early stages of the septic process and to predict its lethality, to correctly assess the animal's condition and to optimize the therapeutic strategy for septic animals. The prognosis of the outcome of septic complications in feline panleukopenia was based on the study of case histories of 10 cats with the diagnosis of panleukopenia, registered when the animals were admitted to the hospital. Confirmation of viral disease was based on clinical signs of the disease - apathy, vomiting, diarrhea, morphological and biochemical blood tests, positive PCR-test for feline panleukopenia virus. The study was conducted at the Department of Epizootology and Organization of Veterinary Business of the Moscow State Academy of Veterinary Medicine and Biotechnology - K. I. Skryabin MVA. Statistical significance of the prognosis was evaluated by correlation and regression analysis of the indicators in a bundle (PIRO-Disease Outcome Score; SAPS-Disease Outcome Score; PIRO-Disease Outcome Score; PIRO-SAPS Score). The calculated parameters of the prognostic model of the disease outcome in cats diagnosed with panleukopenia explain the reliable dependence on the number of scores on the PIRO scale at the initial examination of animals by 86.1%.

sepsis, cats, panleukopenia, scores, PIRO, SAPS, correlation-regression analysis

01 Introduction

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02 References

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Citation Links

[1]2024. PIRO AND SAPS SCALES FOR PREDICTING DISEASE OUTCOME IN CATS. Izdenister natigeler. 3(103) (Sep. 2024), 40–49. DOI:https://doi.org/10.37884/3-2024/05.

(1)PIRO AND SAPS SCALES FOR PREDICTING DISEASE OUTCOME IN CATS. Izdenister natigeler 2024, No. 3(103), 40-49. https://doi.org/10.37884/3-2024/05.

PIRO AND SAPS SCALES FOR PREDICTING DISEASE OUTCOME IN CATS. (2024). Izdenister Natigeler, 3(103), 40-49. https://doi.org/10.37884/3-2024/05

PIRO AND SAPS SCALES FOR PREDICTING DISEASE OUTCOME IN CATS. Izdenister natigeler, [S. l.], n. 3(103), p. 40–49, 2024. DOI: 10.37884/3-2024/05. Disponível em: https://natsus.kaznaru.edu.kz/index.php/research/article/view/680. Acesso em: 15 sep. 2026.

“PIRO AND SAPS SCALES FOR PREDICTING DISEASE OUTCOME IN CATS”. 2024. Izdenister Natigeler, no. 3(103) (September): 40-49. https://doi.org/10.37884/3-2024/05.

“PIRO AND SAPS SCALES FOR PREDICTING DISEASE OUTCOME IN CATS” (2024) Izdenister natigeler, (3(103), pp. 40–49. doi:10.37884/3-2024/05.

[1]“PIRO AND SAPS SCALES FOR PREDICTING DISEASE OUTCOME IN CATS”, Izdenister natigeler, no. 3(103), pp. 40–49, Sep. 2024, doi: 10.37884/3-2024/05.

“PIRO AND SAPS SCALES FOR PREDICTING DISEASE OUTCOME IN CATS”. Izdenister Natigeler, no. 3(103), Sept. 2024, pp. 40-49, https://doi.org/10.37884/3-2024/05.

“PIRO AND SAPS SCALES FOR PREDICTING DISEASE OUTCOME IN CATS”. Izdenister natigeler, no. 3(103) (September 30, 2024): 40–49. Accessed September 15, 2026. https://natsus.kaznaru.edu.kz/index.php/research/article/view/680.

1.PIRO AND SAPS SCALES FOR PREDICTING DISEASE OUTCOME IN CATS. Izdenister natigeler [Internet]. 2024 Sep. 30 [cited 2026 Sep. 15];(3(103):40-9. Available from: https://natsus.kaznaru.edu.kz/index.php/research/article/view/680

1.PIRO AND SAPS SCALES FOR PREDICTING DISEASE OUTCOME IN CATS. Izdenister natigeler. 2024;(3(103):40-49. doi:10.37884/3-2024/05

[1] 1. Predicting Leptospirosis Outcomes in Dogs with the Simplified Acute Physiology Score [Text] / S. Laptev, N. Pimenov, S. Pozyabin [et al.] // Advancements in Life Sciences. – 2024. – Vol. 11, No. 1. – P. 173-181. – EDN PXTEYW.

[2] 2. Prognosis of purulent-septic pathologies in veterinary propaedeutics of generalization of bacterioses on a cat model [Text] / S. Laptev, N. Pimenov, S. Marzanova, K. Permyakova // AIP Conference Proceedings: International Conference “Sustainable Development: Veterinary Medicine, Agriculture, Engineering and Ecology” (VMAEE2022), Moscow, Russia, 18–20 апреля 2022 года. Vol. 2817. – Moscow, Russia: AIP Publishing, 2023. – P. 020047. – DOI 10.1063/5.0148361. – EDN VDTMVQ.

[3] 3. Катионные белки гранулоцитов в прогностике гнойно-септических патологий в ветеринарной пропедевтике генерализации бактериозов [Текст]/ Н. В. Пименов, С. В. Лаптев, С. Н. Марзанова [и др.]. – Москва: Издательский дом «НАУЧНАЯ БИБЛИОТЕКА», 2023. – 172 с. – ISBN 978-5-907672-71-0.

[4] 4. Лаптев, С. В. Прогноз септических патологий в ветеринарной пропедевтике на модели панлейкопении кошек [Текст]/ С. В. Лаптев, Н. В. Пименов, Х. С. Горбатова // Ветеринария, зоотехния и биотехнология. – 2022. – № 11. – С. 52-58. – DOI 10.36871/vet.zoo.bio.202211007. – EDN IBOFHC.

[5] 5. Модель PIRO как комплексная оценка септических осложнений в ветеринарной пропедевтике / Н. В. Пименов, С. В. Лаптев, С. Н. Марзанова, К. Ю. Пермякова // Ветеринария, зоотехния и биотехнология. – 2022. – № 4. – С. 6-15. – DOI 10.36871/vet.zoo.bio.202204001. – EDN ZDLBVS.

[6] 6. Эвристические подходы к оценкам риска и прогнозам развития сепсиса у собак / С. В. Лаптев, Н. В. Пименов, С. Н. Марзанова [и др.] [Текст] // Международный вестник ветеринарии. – 2023. – № 3. – С. 35-50. – DOI 10.52419/issn2072-2419.2023.3.35. – EDN TNDYPT.

[7] 7. Патогенез и маркеры сепсиса [Текст]/ С. В. Лаптев, Н. А. Татарникова, К. А. Сидорова, О. В. Новикова // Известия сельскохозяйственной науки Тавриды. – 2023. – № 35(198). – С. 182-197. – EDN OBFCRQ.

[8] 8. Сепсис - терминология и критерии диагностики: эволюция взглядов на проблему [Текст] / М. А. Бабаев, Н. Ю. Тарасова, Т. М. Бирг, О. В. Дымова // Клиническая и экспериментальная хирургия. Журнал имени академика Б.В. Петровского. – 2016. – Т. 4, № 2(12). – С. 35–46.

[9] 9. Bone R.C. Sepsis syndrome: a valid clinical entity [Text] / Bone R.C., Fisher Jr. C.J., Clemmer T.P. // Crit. Care Med. 1989. Vol. 17. P. 389-393.

[10] 10. Sprung C.L. An evaluation of systemic inflammatory response syndrome signs in the Sepsis Occurrence in Acutely ill Patients (SOAP) study [Text]/ Sprung C.L., Sakr Y., Vincent J.L. // Intensive Care Med. 2006. Vol. 32. P. 421–427.

[11] 11. Lai N.A. The predictive ability of a weighted systemic inflammatory response syndrome score for microbiologically confirmed infection in hospitalised patients with suspected sepsis [Text] / Lai N.A., Kruger P. // Crit. Care Resusc. 2011. Vol.13. P. 146-150.

[12] 12. Dellinger R. P. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock [Text] / Dellinger R. P., Levy M. M., Rhodes A. // Intensive Care Med. 2012. Vol. 39. P. 165–228.

[13] 13. Vincent J.L. Sepsis definitions: time for change [Text] / Vincent J.L., Opal S.M., Marshall J.C.// Lancet. 2013. Vol. 381. P. 774-775.

[14] 14. Cecconi M., Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine [Text] / Cecconi M., De Backer D., Antonelli M // Intensive Care Medicine. 2014. Vol. 40. P. 1795–1815.

[15] 15. Singer M. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) [Text] / Singer M., Deutschman C.S., Seymour C.W. // JAMA. 2016. Vol. 315 (8). P. 801–810.

[16] 16. Бунятян А.А. Руководство по кардиоанестезиологии и интенсивной терапии. [Текст] /Бунятян А.А., Трекова Н. А., Еременко А. А. // М.: МИА, 2015. 704 с.