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STOCK-RAISING AND VETERINARY

DIAGNOSIS OF CHLAMIDIA AND ANALYSIS OF THE ASSOCIATION OF POLYMORPHISMS RESISTANT TO CHLAMYDIA

B.E. Nurgaliev 1 , I.S. Beishova 1 , A.Zh. Zholdasbekova 1

1 NJSC “Zhangir Khan West Kazakhstan Agrarian Technical University”, Uralsk, Kazakhstan

doi.org/10.37884/4-2022/01 pp. 5-13 Admitted 10.10.2022 Published 30.12.2022

Abstract

An important step in increasing the genetic potential of productivity of farm animals together with marker-associated breeding activities for veterinary medicine is the use of genetic markers of resistance to bacterial infections. At the same time, due to the diagnosis of infectious diseases, including chlamydia, using modern techniques, analysis of treatment costs and associations of polymorphisms resistant to chlamydia, reduction of losses from mortality, abortions and selection of sick animals, the profitability of the farm increases. In this work, chlamydia infection was diagnosed in the studied animals, animal genotypes were determined, and the frequency of mutations in these animals was analyzed, the association of each individual polymorphism with resistance to bacterial infections was analyzed. As a result of the research work, the genotypes of animals in the research groups were identified. The biological models of these animals are monomorphic in bTLR4-BstU1 and bTLR6-Tag1 polymorphisms. For this reason, two polymorphic genes MBL1-HaeIII and LTF-Ecori were included in the study, which were associated with bacterial infections of cattle; it was also found that the frequencies of genotypes observed in the group of animals infected with chlamydia have statistically significant deviations from theoretically expected in accordance with the Hardy-Weinberg law. According to TLR9-BfaI polymorphism, a large number of TLR9-BfaIAG heterozygotes are observed, and according to LTF-EcoRI-LTF-Ecoriab heterozygotes, which characterizes a decrease in the resistance of the TLR9-BfaIAG and LTF-EcoRIAB genotypes to chlamydia; TLR9-Bfaiaa and MBL1-Naeiiiss hepotypes were identified as a genetic marker of high resistance to chlamydia; TLR9-BfaIAG and MBL1-Naiiyix genotypes have been identified as a genetic marker of a high risk of chlamydia.

holstein breed, chlamydia, TLR4, TLR6, TLR9 gene polymorphism, genotype, ELISA method, alleles, heterozygote

01 Introduction

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02 References

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Citation Links

[1]2022. DIAGNOSIS OF CHLAMIDIA AND ANALYSIS OF THE ASSOCIATION OF POLYMORPHISMS RESISTANT TO CHLAMYDIA. Izdenister natigeler. 4 (96) (Dec. 2022), 5–13. DOI:https://doi.org/10.37884/4-2022/01.
(1)DIAGNOSIS OF CHLAMIDIA AND ANALYSIS OF THE ASSOCIATION OF POLYMORPHISMS RESISTANT TO CHLAMYDIA. Izdenister natigeler 2022, No. 4 (96), 5-13. https://doi.org/10.37884/4-2022/01.
DIAGNOSIS OF CHLAMIDIA AND ANALYSIS OF THE ASSOCIATION OF POLYMORPHISMS RESISTANT TO CHLAMYDIA. (2022). Izdenister Natigeler, 4 (96), 5-13. https://doi.org/10.37884/4-2022/01
DIAGNOSIS OF CHLAMIDIA AND ANALYSIS OF THE ASSOCIATION OF POLYMORPHISMS RESISTANT TO CHLAMYDIA. Izdenister natigeler, [S. l.], n. 4 (96), p. 5–13, 2022. DOI: 10.37884/4-2022/01. Disponível em: https://natsus.kaznaru.edu.kz/index.php/research/article/view/144. Acesso em: 15 sep. 2026.
“DIAGNOSIS OF CHLAMIDIA AND ANALYSIS OF THE ASSOCIATION OF POLYMORPHISMS RESISTANT TO CHLAMYDIA”. 2022. Izdenister Natigeler, no. 4 (96) (December): 5-13. https://doi.org/10.37884/4-2022/01.
“DIAGNOSIS OF CHLAMIDIA AND ANALYSIS OF THE ASSOCIATION OF POLYMORPHISMS RESISTANT TO CHLAMYDIA” (2022) Izdenister natigeler, (4 (96), pp. 5–13. doi:10.37884/4-2022/01.
[1]“DIAGNOSIS OF CHLAMIDIA AND ANALYSIS OF THE ASSOCIATION OF POLYMORPHISMS RESISTANT TO CHLAMYDIA”, Izdenister natigeler, no. 4 (96), pp. 5–13, Dec. 2022, doi: 10.37884/4-2022/01.
“DIAGNOSIS OF CHLAMIDIA AND ANALYSIS OF THE ASSOCIATION OF POLYMORPHISMS RESISTANT TO CHLAMYDIA”. Izdenister Natigeler, no. 4 (96), Dec. 2022, pp. 5-13, https://doi.org/10.37884/4-2022/01.
“DIAGNOSIS OF CHLAMIDIA AND ANALYSIS OF THE ASSOCIATION OF POLYMORPHISMS RESISTANT TO CHLAMYDIA”. Izdenister natigeler, no. 4 (96) (December 30, 2022): 5–13. Accessed September 15, 2026. https://natsus.kaznaru.edu.kz/index.php/research/article/view/144.
1.DIAGNOSIS OF CHLAMIDIA AND ANALYSIS OF THE ASSOCIATION OF POLYMORPHISMS RESISTANT TO CHLAMYDIA. Izdenister natigeler [Internet]. 2022 Dec. 30 [cited 2026 Sep. 15];(4 (96):5-13. Available from: https://natsus.kaznaru.edu.kz/index.php/research/article/view/144
1.DIAGNOSIS OF CHLAMIDIA AND ANALYSIS OF THE ASSOCIATION OF POLYMORPHISMS RESISTANT TO CHLAMYDIA. Izdenister natigeler. 2022;(4 (96):5-13. doi:10.37884/4-2022/01